Abstract

VANEGAS-MUNERA, JOHANNA MARCELA; RONCANCIO-VILLAMIL, GUSTAVO  and  JIMENEZ-QUICENO, JUDY NATALIA. Acinetobacter baumannii: Clinical importance, resistance mechanisms and diagnosis. CES Med. [online]. 2014, vol.28, n.2, pp.233-246. ISSN 0120-8705.

Currently Acinetobacter baumannii has become in a microorganisms of great clinical importance. It has an extraordinary capacity to spread in the hospital environment and it has been associated with high mortality rates. Acinetobacter baumannii has acquired different resistance mechanisms to antibiotics with reports resistance to carbapenems, aminoglycosides, quinolones and polymyxins; which has complicated the therapy of the infections caused for this pathogen. The problem is further due to the limitations in the diagnosis and the lack of standardized phenotypic methods to detect specific resistance mechanisms. In Colombia has reported high percentages of resistance to carbapenems, which has reduced therapeutic options. The knowledge of local epidemiology is necessary for establish more assertive control measures

Keywords : Acinetobacter baumannii; Antimicrobial resistance; ß-lactamases; Susceptibility tests; Virulence.

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