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CES Medicina
Print version ISSN 0120-8705
Abstract
AGUIRRE-H, HERNÁN DARÍO; POSADA-L, ANDRÉS FELIPE and APONTE, JORGE ENRIQUE. Congenital deficiency of factor V. CES Med. [online]. 2014, vol.28, n.2, pp.247-252. ISSN 0120-8705.
Blood coagulation factor V (FV) plays a pivotal role in blood coagulation. It is found in both plasma and in platelets and has a profound impact on thrombin generation. Deficiency of this clotting factor due to inherited or acquired conditions results in a broad spectrum of bleeding symptoms. ranging from mucocutaneous bleeding to central nervous system bleeding. We present a case of a 33-year-old woman with abnormal uterine bleeding for several years, not improvement with the management in previous consultations, concluding after several tests a congenital Leiden V factor deficiency
Keywords : Haemorrhagia; International normalized ratio; Deficiency factor V.