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CES Medicina
Print version ISSN 0120-8705
Abstract
AGUIRRE, Lina María; TORO, Ana María; DEL RIO, Delsy Yurledy and RUIZ, Ana Cristina. Lupus erythematosus tumidus in childhood treated with antimalarials. CES Med. [online]. 2018, vol.32, n.2, pp.141-149. ISSN 0120-8705. https://doi.org/10.21615/cesmedicina.32.2.7.
Lupus erythematosus tumidus is a rare dermatosis. It is considered a subtype of chronic cutaneous lupus erythematosus of uncertain pathogenesis, favorable prognosis and rare association with systemic lupus erythematosus. Clinically, it manifests as urticarial-like plaques in photo exposed areas, mainly affecting adults, being extremely rare in pediatric age. Herein, we present two cases of six and nine-year-old male patients with clinical and histological characteristics typical of lupus erythematosus tumidus and poor response to first-line treatment (topical, intralesional steroids and topical calcineurin inhibitors); therefore, it was decided to start systemic therapy with antimalarials, obtaining a very good response.
Keywords : Cutaneous lupus erythematosus; Skin abnormalities; Photosensitivity disorders; Child; Antimalarial drugs.