Abstract

GONZALEZ P., Luis G et al. Pregnancy-associated purpura fulminans (pf). Iatreia [online]. 2005, vol.18, n.3, pp.302-307. ISSN 0121-0793.

PF is a serious cutaneous purpuric disease, associated with an intravascular disseminated coagulation syndrome. Among its known causes, besides those of thrombophilia, are viral and bacterial infections, mostly Neisseria meningitidis. During pregnancy there are alterations in the hemostatic mechanism. However, by themselves, they have not been shown to lead to PF. The case of a 22-year-old woman who developed PF during pregnancy, presumably due to her Escherichia coli urinary tract infection, is presented including clinical, paraclinical, therapeutic and surgical aspects. She recovered but suffered amputation of the distant phalanges of three toes in the left foot.

Keywords : disseminated intravascular coagulation; escherichia coli; heparin; pregnancy; protein c; purpura fulminans.

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