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Revista Colombiana de Reumatología
Print version ISSN 0121-8123
Abstract
SALDARRIAGA RIVERA, Lina María; SANCHEZ-RAMIREZ, Nicolás; RODRIGUEZ-CONDE, Laura and TEJEDOR-RESTREPO, Diana Paola. Macrophage activation syndrome as a result of rheumatological diseases: Report of 4 cases. Rev.Colomb.Reumatol. [online]. 2021, vol.28, n.3, pp.221-226. Epub Jan 18, 2022. ISSN 0121-8123. https://doi.org/10.1016/j.rcreu.2020.04.006.
Macrophage activation syndrome (MAS) is a serious complication of several rheumatic disorders, among which are the systemic juvenile idiopathic arthritis, Still's disease and systemic lupus erythematosus. This syndrome is part of the Acquired Haemophagocytic Lymphohistiocytoses, and is a potentially fatal disease, with difficulty in its identification and a lack of consensus regarding its management. A series of cases are describe of patients with macrophage activation syndrome, explaining their diagnostic process, their relationship with rheumatic diseases, their monitoring, and treatment, as well as the results of different management schemes.
Keywords : Macrophage activation syndrome; Haemophagocytic lymphohistiocytosis; Systemic lupus erythematosus; Antiphospholipid syndrome; Rheumatic diseases; Arthritis.