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Revista Colombiana de Reumatología
Print version ISSN 0121-8123
Abstract
SALDARRIAGA RIVERA, Lina María; MARIN GIRALDO, Christian David and HERNANDEZ VELASCO, Fabián Andrés. Janus kinase inhibitor as a therapeutic option in alopecia areata. Case report. Rev.Colomb.Reumatol. [online]. 2023, vol.30, n.2, pp.162-165. Epub May 16, 2024. ISSN 0121-8123. https://doi.org/10.1016/j.rcreu.2021.05.016.
Alopecia areata (AA) is an autoimmune disease that generates non-scar loss of hair with varying degrees of involvement, including total loss of hair follicles. Despite being a benign entity, it has a great impact on the emotional and psychosocial life of patients. A wide variety of topical and oral treatments are currently available. We present the case of a 24-year-old patient with severe recurrent alopecia areata without response to multiple pre vious treatments, in which a secondary cause was ruled out and the histological diagnosis was confirmed with biopsy. Treatment with tofacitinib, a JAK inhibitor, was started, showing an excellent clinical response after one month of treatment.
Keywords : Alopecia areata; Tofacitinib; Janus kinase.