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Infectio
Print version ISSN 0123-9392
Abstract
RAMIREZ-GARCIA, Nathaly et al. Survival in people living with HIV in the framework the Colombian health system: 2011-2018. Infect. [online]. 2021, vol.25, n.4, pp.276-283. Epub July 19, 2021. ISSN 0123-9392. https://doi.org/10.22354/in.v25i4.960.
Objective:
to describe the seven-year survival and predictors of mortality among people with HIV who were treated in the Colombian health system between 2011 and 2018.
Methods:
64 039 people diagnosed with HIV in Colombia were included. Kaplan-Meier analysis estimated the probability of survival from the date of diagnosis. A Royston Parmar flexible parametric survival model was fitted.
Results:
The overall survival at 7 years was 94.8% (95% CI: 94.5-95.2). Survival was related to sex (men, HR: 1.2; 95% CI: 1.1-1.4; p: 0.010); people ≥50 years of age (HR: 3.1; 95% CI: 1.6-6.3; p: 0.002); subsidized regime (HR: 2.2; 95% CI: 1.9-2.5; p: <0.001); AIDS stage (HR: 2.8; 95% CI: 2.1-3.7; p: <0.001); a detectable viral load (HR: 7.1; 95% CI: 6.0-8.3; p: <0.001); and a CD4+ Lymphocyte count <350 cells/μL (HR: 1.9; 95% CI: 1.4-2.4; p: <0.001).
Conclusion:
The probability of survival of people living with HIV increases when they are diagnosed at a young age, in those with a CD4+ T Lymphocyte count ≥350 cells/μL, an undetectable viral load (<50 copies/mL) and are not in the AIDS stage.
Keywords : Survival Analysis; HIV; CD4 Lymphocyte Count; Viral load.