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Revista de Salud Pública
Print version ISSN 0124-0064
Abstract
GONZALEZ-MARINO, Mario A.. Cost-effectiveness of risk-reducing salpingo-oophorectomy in cases of BRCA1 gene mutation in Colombia. Rev. salud pública [online]. 2018, vol.20, n.2, pp.232-236. ISSN 0124-0064. https://doi.org/10.15446/rsap.v20n2.64866.
Objective
To assess the usefulness of risk reduction salpingo-oophorectomy in cases with mutation of the BRCA1 gene in Colombia.
Material and Methods
Cost-effectiveness analysis in which three processes are incorporated: a. Patients with screening tests for breast and ovarian cancer. b. Risk reduction surgery in the fallopian tubes and ovaries c. Reductive surgery in the fallopian tubes and ovaries with bilateral mastectomy. The outcome is evaluated as the gain in years of survival.
Results
The cohort with risk reduction surgery in the fallopian tubes and ovaries and bilateral mastectomy is the one with the highest gain with 13 years, while the risk reduction surgery in the fallopian tubes and ovaries gain 4.95 years with respect to the follow-up group.
Conclusions
The three options evaluated are acceptable, but of them the one with the greatest gain in survival is the combination of risk-reducing surgery in the fallopian tubes and ovaries with bilateral mastectomy.
Keywords : Cost-benefit analysis; ovarian neoplasms; breast neoplasms; ovariectomy; prophylactic surgical procedures (source: MeSH, NLM).
