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Revista de Salud Pública
Print version ISSN 0124-0064
Abstract
GUTIERREZ-MARTINEZ, Anthony et al. Sustainable anticoagulation in COVID-19: Review of severity prediction and clinical reasoning. Rev. salud pública [online]. 2020, vol.22, n.3, pp.373-380. Epub Feb 03, 2021. ISSN 0124-0064. https://doi.org/10.15446/rsap.v22n3.87321.
Objective
To identify the procoagulant phenomenon in SARS-CoV-2 patients and propose sustainable therapeutic guidance for low-income countries.
Methods
A systematic review was conducted. It identified 5 observational studies from a scrutiny from 78 results. 712 patients were examined and the results were grouped according to mortality and severity. The comparison of the groups was interpreted using descriptive statistics.
Results
D-dimer values were significantly associated with greater severity and mortality. Prothrombin was associated in some observations with higher mortality, but in terms of severity it was inconclusive.
Conclusion
COVID-19 disease has significant procoagulant activity and its timely treatment can alter the prognosis. The explored evidence supports sustainable methods. More evidence is needed to improve management. An early systematic approach to patients with sustainable therapeutic measures tailored to the health system is recommended.
Keywords : Anticoagulation; COVID-19; D-dimer; low-molecular-weight heparin; unfractionated heparin; thrombocytopenia; pulmonary thromboembolism (source: MeSH, NLM).
