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Revista Colombiana de Nefrología
On-line version ISSN 2500-5006
Abstract
CHAVEZ GOMEZ, Wilson Femando; ARIZA GARCIA, Amaury Miguel and RAMOS CLASON, Enrique Carlos. Characterization of thyroid dysfunction in adults with chronic renal disease in dialysis. Rev. colom. nefrol. [online]. 2018, vol.5, n.2, pp.156-165. ISSN 2500-5006. https://doi.org/10.22265/acnef.0.0.312.
Background:
There is a clear relationship between thyroid dysfunction and chronic kidney disease (CKD), which is evidenced by the increase in the prevalence of primary hypothyroidism when the glomerular filtration rate decreases.
Objectives:
Characterize adult patients with thyroid dysfunction and chronic kidney disease on dialysis therapy.
Methods:
An observational, descriptive, cross-sectional study was carried out that characterized and collected laboratory reports of patients >18 years of age with CKD in dialysis therapy of a renal unit of the city of Cartagena/Bolívar with TSH control in 2016.
Results:
350 patients with TSH registry were included, with a median age of 59 years and 49.1% were women. The main cause and comorbidity of CKD was hypertension in 36.3% and hyperpatioidism in 56% respectively. In relation to thyroid dysfunction, 25.4% of the population had TSH levels> 4.5 uIU/mL, of which 5.7% had TSH levels> 10 uIU/mL (hypothyroidism).
Conclusions:
The prevalence of thyroid dysfunction was higher than in the general population, however additional studies with measurement of FT4 are necessary to achieve an adequate categorization.
Keywords : thyroid gland; kidney; kidney failure; chronic; glomerular filtration rate; dialysis; hypothyroidism; thyrotropin.