Resumen

CORREDOR-SANCHEZ, Eugenia  y  CASTILLO, Marcos. The prevalence of squamous intraepithelial lesions amongst patients having atypical glandular cells: Colposcopic and histopathological findings from a reference institution in Bogotá, Colombia. Rev Colomb Obstet Ginecol [online]. 2008, vol.59, n.2, pp.118-123. ISSN 0034-7434.

Objectives: determining the prevalence of intraepithelial squamous lesions and the diagnostic validity of endocervical curettage in patients having cytology reporting atypical glandular cells. Methods: a cross-sectional study was carried out from January 2000 to June 2006 at La Samaritana teaching hospital, this institution being classified as a third-level hospital in Bogotá, Colombia. Selection criteria consisted of complete information being available regarding the patients’ cytology concerning having atypical glandular cells, colposcopy and endocervical curettage. SPSS statistical software (version 15) was used for processing the data. Results: the records of 105 women having had a positive cytology for atypical glandular cells were analysed. Cervical intraepithelial lesion prevalence was 53% in women having atypical glandular cells, 7% of them having high grade intraepithelial squamous lesions and 46.5% low grade lesions. Endocervical curettage revealed that 86.7% were negative for lesions and 13.3% had low grade intraepithelial lesions. 22 samples provided insufficient data. Histopathological exocervical epithelium results proved negative in 46.5% of cases; a similar 46.5% had low grade intraepithelial lesions and 7% high grade lesions. Agreement between exocervical biopsy and endocervical curettage resulted in a 0.07 Kappa score. Conclusion: There was a high prevalence of intraepithelial cervical lesion, being found in 53% of women having atypical cells. None of these women had positive result for squamocellular carcinoma or adenocarcinoma.

Palabras clave : atypical glandular cells; squamous intraepithelial lesions; endocervical curettage; colposcopy.

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