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Revista Colombiana de Obstetricia y Ginecología
versión impresa ISSN 0034-7434versión On-line ISSN 2463-0225
Resumen
RENDON-BECERRA, César Augusto; GOMEZ-BRAVO, Alex; ERAZO-NARVAEZ, Andrés Felipe y ORTIZ-MARTINEZ, Roberth Alirio. Diagnostic accuracy of a hysteroscopic score for the detection of endometrial cancer in patients with postmenopausal bleeding and endometrial thickening. Rev Colomb Obstet Ginecol [online]. 2020, vol.71, n.3, pp.237-246. Epub 30-Sep-2020. ISSN 0034-7434. https://doi.org/10.18597/rcog.3445.
Objective:
To assess the diagnostic accuracy of hysteroscopic scores in endometrial cancer.
Materials and methods:
Diagnostic accuracy study assembled within a cross-sectional study that included patients with postmenopausal bleeding and endometrial thickening greater than 5 mm in whom hysteroscopy was performed and then compared with endometrial biopsy as the diagnostic gold standard, in two high complexity hospitals. Clinical, sociodemographic variables, as well as hysteroscopic scores and the results of endometrial tissue histopathology were measured. Sensitivity and specificity, likelihood ratios and area under the curve with their respective confidence intervals were estimated in the analysis.
Results:
With a 9 % prevalence of endometrial
cancer, the hysteroscopic assessment system was shown to have 75 % sensitivity (95 % CI; 30.1- 95.43), 95,1 % specificity (95 % CI; 83.9-98.7), a positive likelihood ratio of 15.38 (95 %; CI 3.55- 66.56), a negative likelihood ratio of 0.26 and area under the curve of 85 %.
Conclusion:
The standardized hysteroscopic assessment system was found to have an acceptable sensitivity for screening in patients with postmenopausal bleeding and endometrial thickening (≥ 5 mm). Further studies with larger sample sizes are required in order to arrive at a more precise estimation of the operational characteristics of the hysteroscopic assessment system for the detection of endometrial cancer.
Palabras clave : Uterine hemorrhage; hysteroscopy; endometrial neoplasms; postmenopause..