Servicios Personalizados
Revista
Articulo
Indicadores
- Citado por SciELO
- Accesos
Links relacionados
- Citado por Google
- Similares en SciELO
- Similares en Google
Compartir
Iatreia
versión impresa ISSN 0121-0793
Resumen
MAYA-RICO, Ana María y CARDONA-CASTRO, Nora. Chronic mucocutaneous candidiasis: a look at genetic understanding. Iatreia [online]. 2018, vol.31, n.4, pp.393-399. ISSN 0121-0793. https://doi.org/10.17533/udea.iatreia.v31n4a06.
Chronic mucocutaneous candidiasis is an infectious phenotype characterized by recurrent or persistent infections in the skin, nails and mucous membranes produced by Candida sp. This is secondary to any alteration in the antifungal immunity, in which not only the production of IL-17, but any defect in the differentiation of the T lymphocytes towards their TH17 profile, play a fundamental role and will unchain a susceptibility to this infection; that depending on the genetic etiology, can be a syndromic manifestation with other associated infectious and endocrinological clinical characteristics. Here, we review in a practical, clear and concise manner, the genetic defects so far found to be involved in the appearance of chronic mucocutaneous candidiasis.
Palabras clave : Autoimmune Polyendocrinopathy; Chronic Mucocutaneous Candidiasis; Factor de Transcripción STAT1; Genetics.