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Revista U.D.C.A Actualidad & Divulgación Científica
versión impresa ISSN 0123-4226
Resumen
CORREDOR-MATUS, José Ricardo; RIVEROS-SANABRIA, Fernando y CORREDOR-MESA, Laura Tatiana. Heart rate variability in patients with Chagas' heart disease. rev.udcaactual.divulg.cient. [online]. 2020, vol.23, n.2, e1197. Epub 30-Jul-2020. ISSN 0123-4226. https://doi.org/10.31910/rudca.v23.n2.2020.1197.
The prevalence by Trypanosoma cruzi of 436,000 inhabitants in Colombia is estimated, with annual cases of 5,250, in an exposed population of 4,792,000 inhabitants. Heart rate variability (HRV) is the time interval of a beat in a given time analysis. Its analysis allows to determine the sympathetic-vagal balance indirectly. This study analyzed the temporal and non-linear variables in 19 Chagasic patients and 19 controls, using a high-resolution polygraph and the Kubios software. The variable Standard Deviation of the RR Interval (SDRR) in the control population showed an average of 56.23±29.6ms vs 40.62±30.1ms in the seropositive; The Square Root of the Sum of the Square Differences of all Adjacent intervals (RMSSD) was 34.31±21.01ms and 31.94±37.33ms for controls and Chagas respectively. The number of consecutive RR intervals that differ by more than 50ms from each other (NN50) in controls 76.47±78.3 beats vs 13.47±36.8 for seropositives corresponding to the percentage of NN50 (pNN50) 12.3±13.3% and 2.64±6.0%, respectively for the same order of the groups. Approximate Entropy (ApEn) values were 1,249±0,134 for controls and 0,959±0,325 for seropositive, and for Sample Entropy (SampEn) it was 1,358±0,264 and 1,102±0,385 for controls and chagasics respectively. Greater irregularity of HRV was found in controls, which reflects a better state of health.
Palabras clave : Chagas; Heartbeat; Entropy; Vagus nerve; Temporal variable.