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Revista Colombiana de Ciencias Químico - Farmacéuticas
versión impresa ISSN 0034-7418
Resumen
RODRIGUEZ RODRIGUEZ, Luis E et al. Experimental basic research to define critical parameters in the process of obtaining concentrated solutions of propolis (CSP). Rev. colomb. cienc. quim. farm. [online]. 2016, vol.45, n.2, pp.179-200. ISSN 0034-7418. https://doi.org/10.15446/rcciquifa.v45n2.59935.
Introduction: SCP's processes of obtaining Propolis have been developed by different investigators so much nationally like international. Objective: To define SCP's critical parameters of the process of obtaining, to increment the performance and the quality of this product and his by-products. Methods: Pichansky's method of purification, with some modifications was utilized to the variables following: Relation mass/volume, concentration of ethanol and the time of agitation. The utilized materials are guaranteed for the Quality Management System of the Center. Results: The variants #2 and #4 of the process of extraction, utilized to scale of laboratory, gave better results, obtaining percentage's range solid totals between 12.4 and 14.3 %, with a performance between 48.5 and 83.0 %. Variant #4 was selected in order to make the experimental lots at reactor scale. Conclusions: the studied variables: Time agitation, concentration of ethanol and the relation mass/volume, as well as the percentage of the solid totals, the percentage of the performance and organoleptic properties, of variants #2 and #4, allowed carrying out the objectives proposed in this investigation. These variables responded positively in the variants and can be used in the elaboration of the productive lots considering the concentration of alcoholic propolis' solutions required.
Palabras clave : Solutions concentrated of propolis; method of obtaining; experimental investigation; parameters of quality.