Servicios Personalizados
Revista
Articulo
Indicadores
Citado por SciELO
Accesos
Links relacionados
Citado por Google
Similares en SciELO
Similares en Google
Compartir
Acta Neurológica Colombiana
versión impresa ISSN 0120-8748versión On-line ISSN 2422-4022
Resumen
PACHAJOA, Harry et al. Neurozika, from the basic science to the clinical practice. Literature review. Acta Neurol Colomb. [online]. 2021, vol.37, n.1, suppl.1, pp.27-34. Epub 20-Mayo-2021. ISSN 0120-8748. https://doi.org/10.22379/24224022321.
Zika virus (ZV) is a member of the Flaviviridae family and part of the Spondweni serocomplex, mainly transmitted by the Aedes vector family. The first case report of an unknown exanthematous disease was identified in Brazil and subsequently, it was recognized as ZV infection in December 2014. By May 2015, ZV spread throughout Brazil and in November 2015 the association with microcephaly and congenital abnormalities during pregnancy, was confirmed. Subsequently, multiple neurological alterations have been reported among the pediatric population such as microcephaly, corticospinal alterations, neuromuscular symptoms, dyskinesia, chorioretinal atrophy with macular coloboma, nystagmus, congenital glaucoma, sensorineural hearing loss and cortical dysplasia, ventriculomegaly, calcifications, hypoplasia of the brain stem and cerebellum with afection of the vermis, white matter alteration, dysgenesis of the corpus callosum and hydrocephalus, Dandy Walker malformation, thinning of the thoracic portion and spinal cord may explain the clinical signs of congenital ZV syndrome. Also, Guillain-Barre syndrome has been documented in adults with an incidence of 2 to 3 cases per 10,000 infections and, less frecuently, myelitis and encephalitis have been reported. Additionally, behaviour impairments have been described as well as decreased level of consciousness, seizures and meningism. Finally, the least frequent manifestations reported so far are acute disseminated encephalomyelitis, peripheral facial palsy and myeloradiculopathy.
Palabras clave : zika virus infection; zika virus; microcephaly; Guillain-Barre syndrome; hearing loss (MeSH).