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Revista colombiana de Gastroenterología
versión impresa ISSN 0120-9957versión On-line ISSN 2500-7440
Resumen
GARCIA-DUPERLY, Rafael et al. Characteristics of Inflammatory Bowel Disease Compared to Other National Centers in Colombia. Rev. colomb. Gastroenterol. [online]. 2022, vol.37, n.1, pp.48-56. Epub 19-Mayo-2022. ISSN 0120-9957. https://doi.org/10.22516/25007440.752.
Introduction:
Inflammatory bowel disease (IBD) is an immune-mediated disease whose incidence in Latin America has increased in recent years.
Aim:
To analyze the demographic and clinical characteristics of patients with IBD treated in a university hospital and present the epidemiological data compared to other centers in Colombia.
Patients and methods:
Descriptive study of patients with IBD (1996-2019) at the Hospital Universitario Fundación Santa Fe de Bogotá. Analysis of data from centers in Medellín, Cali, Bogotá, and Cartagena.
Results:
Of 386 patients, 277 presented with ulcerative colitis (UC), 102 with Crohn’s disease (CD), and seven with unclassifiable colitis. IBD was more frequent in women (53 %). Mortality was less than 1 %. The involvement of UC was mainly pancolitis (42.6 %). The greater the extent of the disease, the higher the hospitalization and surgery rates (OR 3.70, P < 0.01). Thirteen percent of patients with UC received biologics. Compromise due to CD was mainly ileocolonic (43.6 %) and ileal (43.6 %). The predominant clinical pattern of CD was structuring (50%). Forty-five percent received biologicals and 56 % surgery. Primary sclerosing cholangitis (PSC) was found in 4 % of patients (n = 15). Two patients with PSC developed colorectal cancer (OR 4.18; p 0.008), while 13 patients with UC developed colon cancer and seven dysplastic changes. Three patients with CD developed colon cancer.
Conclusions:
The results were compared to other reference centers. We found similar trends in the clinical behavior and treatment of IBD, with higher hospitalization and surgery rates in our cases.
Palabras clave : Inflammatory bowel disease; Colombia; ulcerative colitis; Crohn’s disease; phenotype.