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Revista de la Universidad Industrial de Santander. Salud
versión impresa ISSN 0121-0807versión On-line ISSN 2145-8464
Resumen
ABUABARA-FRANCO, Emilio et al. Anticoagulation in patients with SARS-CoV-2 Infection/COVID-19. Rev. Univ. Ind. Santander. Salud [online]. 2020, vol.52, n.4, pp.422-430. Epub 30-Sep-2020. ISSN 0121-0807. https://doi.org/10.18273/revsal.v52n4-2020009.
Introduction:
COVID-19 is an infectious disease caused by the RNA SARS-CoV-2 virus, with a high rate of infection and a heterogeneous clinical course. There is evidence that in the advanced phase of COVID-19 there is an increased risk of disseminated intravascular coagulation. Therefore, heparin management should be considered as a therapeutic strategy.
Objectives:
Our main objective is to show the most relevant literature available, with reference to the usefulness of anticoagulation in the management of hypercoagulability in patients with COVID-19 and severe manifestations.
Methodology:
A narrative review was performed from the advanced search with the terms DeSC: Coronavirus Infections; SARS-CoV; Blood Coagulation; Disseminated intravascular coagulation; Multiple organic dysfunction; Sepsis; Systemic inflammatory response syndrome; Acute kidney injury. The Clinical Key, Embase, PubMed and Ovid search engines were used, obtaining a total of 143 results, among original articles, case reports, case series and literature reviews, a total of 56 articles were selected that were used to the preparation of this topic review.
Conclusions:
Heparin management should be considered as a therapeutic strategy. We continue with the need for future studies that investigate questions in the hospitalized COVID-19 patient, especially defining, evaluating risk / benefit, which is justified or not with respect to full anticoagulation in some specific patients with COVID-19.
Palabras clave : Coronavirus infections; SARS-CoV; Blood coagulation; Disseminated intravascular coagulation; Multiple organic dysfunction; Sepsis; Systemic inflammatory response syndrome; Acute kidney injury.