Resumen

GAVIRIA ARIAS, Duverney  y  CABALLERO MENDEZ, Lyda Cenobia. Fibroin from silkworm (Bombyx mori L ) as biomaterial used in regenrative medicine process based on tissue engineering. Revista médica Risaralda [online]. 2015, vol.21, n.1, pp.38-47. ISSN 0122-0667.

Tissue regeneration using cells, scaffolds and appropriate growth factors is a key approach in therapy for tissue or organs regeneration. The fibroin from silk has been shown to be effectively used as a scaffold material in these treatments. Silk fibers are obtained from various animal sources, such as spiders, silkworms, scorpions, mites and flies. The silk extracted from silkworm's (Bombyx mori L.) cocoons, is characterized by its excellent mechanical properties, biocompatibility and biodegradability this characteristics makes silk be a suitable source for the development of biomedical devices. The unique combination of elasticity, strength and compatibility with mammalian cells made of silk fibroin attractive for tissue engineering material. This review addresses the processing of silk fibroin in different forms of biomaterials, applications, advantages and limitations as a biomaterial scaffold in tissue engineering for bone, vascular tissues, skin, cartilage, ligaments, tendons, heart tissue, nervous , eye and bladder

Palabras clave : Biomaterial; Fibroin; Tissue engineering; Regenrative medicine.

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