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Revista colombiana de Gastroenterología
versión impresa ISSN 0120-9957versión On-line ISSN 2500-7440
Resumen
VARGAS-MARCACUZCO, Henry Tomas et al. Immunoglobulin G4-Related Disease, A Diagnosis to Take into Account: About a Case. Rev. colomb. Gastroenterol. [online]. 2023, vol.38, n.4, pp.521-528. Epub 26-Feb-2024. ISSN 0120-9957. https://doi.org/10.22516/25007440.978.
Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated and multisystemic condition associated with developing fibroinflammatory lesions in any organ. The diagnosis is made based on the sum of clinical, serological, radiological, and histopathological criteria; however, this is often difficult due to its similarity to neoplasms, infections, or other immune-mediated diseases. Treatment is based on corticosteroids, in a possible combination with immunomodulators. The present case concerns a 59-year-old man with a history of jaundice syndrome and weight loss, admitted for suspected malignant neoplasia of the bile duct. Imaging revealed stricture with dilation of the intrahepatic bile ducts, prominent pancreas, pancreatic duct stricture, and nodular renal lesions. Due to the history of left submandibulectomy two years before the current disease and histology compatible with Küttner’s tumor, plus the high IgG4 serum values, the diagnosis of IgG4-RD was established. He started treatment with corticosteroids and was asymptomatic during follow-up.
Palabras clave : IgG4-related disease; autoimmune pancreatitis; immunoglobulin G4.