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Acta Neurológica Colombiana
versión impresa ISSN 0120-8748
Resumen
RODRIGUEZ GONZALEZ, Miguel y DA CUNA CARRERA, Iria. Deep brain stimulation of internal globus pallidus in Tourette syndrome. Acta Neurol Colomb. [online]. 2018, vol.34, n.2, pp.146-155. ISSN 0120-8748. https://doi.org/10.22379/24224022204.
INTRODUCTION:
Gilles de la Tourette syndrome is a neuropsyquiatric disorder characterized by tics and comorbidities which starts during the infancy. Deep brain Stimulation, accepted as treatment for other diseases, it is reserved for severe cases and pharmacoresistant patients, even though it still remains on the experimental field for this pathology. The main aim of this review is to analyse the current scientific bibliography about Deep brain Stimulation of the Globus Pallidus Internus on the reduction of tics and associated comorbidities from Gilles de la Tourette Syndrome.
MATERIAL AND METHODS:
A systematic review of several scientific articles was done checking (February-March, 2017) MedLine, PubMed, Scopus, Web of Science and Cochrane databases. We have restricted the search to all those articles published from 2012 to 2017, written in English and done with humans, excluding those which were reviews, letters to the editor or not focussed on the subject of the study.
RESULTS:
In general, the outcomes shows significant improvements in almost the totality of patients but the lack of randomised controlled trials with higher samples, the shortage of reliable results and the lack of awareness of the physiopathology and the ideal target to stimulate, don't allow this technique to enjoy scientific evidence enough to be accepted as part of the treatment for this hyperkinetic disorder.
Palabras clave : Neurology; Globus Pallidus; Tics; Deep brain Stimulation; Tourette Syndrome; Treatment Qutcome (MeSH).