Resumo

CARVAJAL-CASTRILLON, Julián; ANDRADE MACHADO, René; AGUIRRE-ACEVEDO, Daniel Camilo  e  MONTOYA ARENAS, David Andrés. Autobiographical memory in patients with temporal lobe epilepsy by hippocampal sclerosis. Acta Neurol Colomb. [online]. 2016, vol.32, n.2, pp.100-107. ISSN 0120-8748.

Introduction: The temporal lobe epilepsy (TLE) is usually associated with memory disorders. Patients with epilepsy probably will have difficulties in the autobiographical memory, mainly in cases where the etiology is for hippocampal sclerosis (HS) Objective: Determine the possible impairments of autobiographical memory in patients with temporal lobe epilepsy by hippocampal sclerosis compared to healthy subjects. Materials and methods: The sample was composed by 25 patients diagnosed with TLE by HS using neuroimaging, and where contrasted with a control group composed by 15 healthy subjects. Patients who previously were evaluated by neurology and neuropsychology, performed the autobiographical memory interview to test the semantic personal memory performance and autobiographical incidents. In order to compare autobiographical memory in both groups, the U test from Mann Whitney was used and the size of the no parametric effect was calculated. Results: he patients presented difficulties remembering personal semantic information in the last 5 years and had relevant alterations remembering autobiographical incidents related to childhood, adulthood, and recent life. Conclusion: The results confirmed the difficulties of patients with TLE by HS to activate memories from the hippocampus for evoking and experimenting again detailed autobiographical incidents from their personal history.

Palavras-chave : Retrograde amnesia; Isolated Retrograde Amnesia; epilepsy; temporal lobe epilepsy; hippocampal sclerosis; neuropsychology.

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