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Revista de la Facultad de Medicina
versão impressa ISSN 0120-0011
Resumo
MONTANA, Andrea et al. Update on polycystic kidney disease. rev.fac.med. [online]. 2018, vol.66, n.1, pp.107-116. ISSN 0120-0011. https://doi.org/10.15446/revfacmed.v66n1.60760.
Introduction:
Polycystic kidney disease (PKD) is a common genetic disease in which cystic lesions develop and progressively replace the renal parenchyma. This is a cause of end-stage kidney disease and a common indication for dialysis and kidney transplantation. These disease presents in two forms, which can be differentiated by their inheritance patterns: autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD).
Objective:
To present a brief account of the most relevant aspects of kidney disease: epidemiology, pathophysiology, diagnosis, clinical manifestations, treatment and prognosis.
Materials and methods:
Systematic literature review conducted in the PubMed, Lilacs, UptoDate and Medline databases with the following terms: polycystic kidney diseases, autosomal dominant polycystic kidney and autosomal recessive polycystic kidney.
Results:
271 articles were found and 64 were chosen based on their relevance.
Conclusions:
All autosomal polycystic kidney disease patients with stage 5 chronic kidney disease should be considered for transplantation, since it is not contraindicated in most cases.
Palavras-chave : Polycystic Kidney Diseases; Autosomal Dominant Polycystic Kidney; Autosomal Recessive Polycystic Kidney (MeSH).