SciELO - Scientific Electronic Library Online

 
vol.68 número1Use of non-pharmacological interventions during urinary catheter insertion for reducing urinary tract infections in non-immunocompromised adults. A systematic reviewCumulative incidence of lethal congenital anomalies in Peru índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

  • Em processo de indexaçãoCitado por Google
  • Não possue artigos similaresSimilares em SciELO
  • Em processo de indexaçãoSimilares em Google

Compartilhar


Revista de la Facultad de Medicina

versão impressa ISSN 0120-0011

Resumo

RAMIREZ-CHEYNE, Julián. Charaterization of prenatal exposure variables in a group of children aged 0-5 years with congenital heart defect treated in Cali, Colombia. The importance of folic acid. rev.fac.med. [online]. 2020, vol.68, n.1, pp.34-43. ISSN 0120-0011.  https://doi.org/10.15446/revfacmed.v68n1.69885.

Introduction:

Congenital heart defects (CHD) have an estimated prevalence of 4 to 9 cases per 1 000 births, and they have a significant impact on child morbidity and mortality. This prevalence variability has been attributed to regional differences in terms of genetic and environmental factors, among others.

Objective:

To obtain data on prenatal exposure variables of patients with CHD treated in Cali, Colombia.

Materials and methods:

A survey was administered to the mothers of 30 children aged 0 to 5 years with CDH treated in 2 health institutions of Cali, Colombia. The instrument was oriented to collect data on multiple prenatal exposure variables, and data collected were entered into an Excel database in order to analyze them using descriptive statistics.

Results:

Several types of exposure potentially associated with having CHD were found, including altered body mass index, inadequate administration of folic acid, and being exposed to X-rays, vitamin A, alcohol and tobacco.

Conclusion:

Insufficient or untimely administration of folic acid could facilitate the development of teratogenic effects of oxidizing agents. Therefore, education programs on the importance of a proper intake of folic acid and the risks derived from exposure to teratogenic agents during pregnancy should be provided to all pregnant women in Cali to reduce the incidence rate of CHD in the city.

Palavras-chave : Congenital Heart Defects; Environmental Exposure; Congenital Abnormalities (MeSH).

        · resumo em Espanhol     · texto em Inglês     · Inglês ( pdf )