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Revista Salud Uninorte
versão impressa ISSN 0120-5552versão On-line ISSN 2011-7531
Resumo
MARTINEZ-MARTINEZ, Adel; LUJAN-PARDO, María del Pilar e LOPEZ-APARICIO, Erich. High risk serotypes of the human papillomavirus (HPV) in patients with exofitic lesions in the oral cavity. Salud, Barranquilla [online]. 2018, vol.34, n.2, pp.420-429. ISSN 0120-5552. https://doi.org/10.14482/sun.34.2.614.58.
Objective:
To determine the prevalence of high-risk serotypes of human papillomavirus in verrucous lesions of the oral cavity in a hospital in Cartagena during July 2014 to July 2015.
Methodology:
An observational, descriptive, prospective study was conducted in 73 patients with verrucous lesions of the oral cavity, in which socio-demographic characteristics, clinical and histopathological diagnosis were determined, and high-risk DNA HPV genotypes 16 and 18 were identified, as well as 12 other high-risk genotypes (31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68), by means of the real-time multiplex PCR test. The study complied with legal and ethical standards. The results were analyzed using descriptive statistics with the Stata program v13.2.
Results:
The prevalence of HPV in the sample studied during the 2014-2015 period was 9.59% (n: 7). In none of the cases positive for HPV in the histopathological study, some high-risk genotype was identified. Serotypes of HPV were more prevalent in patients in the third decade of life (29.5 years, SD ± 10.60), the average age was 62.8 years SD ± 17.74. The population came mainly from the rural area. The most common site was the labial mucosa. A high percentage of participants (87.6%) reported consuming tobacco.
Conclusion:
In the present study no high-risk HPV genotypes were found in the samples evaluated.
Palavras-chave : human papillomavirus; PCR; virus; oral papilloma.