Resumo

QUINTERO GIL, Diana Carolina; OSORIO BENITEZ, Jorge Emilio  e  MARTINEZ-GUTIERREZ, Marlén. Vector competence: Entomological considerations and its implications on the epidemiology of Dengue. Iatreia [online]. 2010, vol.23, n.2, pp.137-145. ISSN 0121-0793.

Vector- borne diseases are a serious problem in public health, especially in tropical and subtropical areas where environmental conditions favor the survival and expansion of vectors into new habitats. Dengue fever is one of the most important vector- borne diseases transmitted by arthropods (arbovirosis) worldwide. The etiologic agent of the disease is the dengue virus, which is transmitted by the bite of bloodsucking Aedes aegypti mosquitoes. The virus- vector interaction is essential for the efficient transmission of the disease, and depends on both, viral factors and vector competence or intrinsic vector capacity to be infected with the virus. Vector competence allows virus replication and subsequent transmission to susceptible hosts. Factors that influence vector capacity include: natural barriers to infection, immunological defenses as well as the presence of receptors for the virus. All these factors in addition to the viral characteristics will determine the degree of transmission. There is a need for a better understanding of the virus- vector relationship and its epidemiological implications. These issues are addressed in this article.

Palavras-chave : Aedes aegypti; Dengue virus; Vector competence.

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