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Revista Colombiana de Reumatología
versão impressa ISSN 0121-8123
Resumo
MALDONADO, Genessis et al. Curvas de intervención y evaluación basadas en FRAX Ecuador. Rev.Colomb.Reumatol. [online]. 2020, vol.27, n.3, pp.155-160. Epub 23-Abr-2021. ISSN 0121-8123. https://doi.org/10.1016/j.rcreu.2020.04.004.
Introduction:
FRAX has been validated and adapted to different countries, covering almost 80% of the world's population, including Ecuador where it was adapted in 2009. The purpose of this study is to elaborate evaluation and intervention curves based on FRAX Ecuador.
Methods:
Using the FRAX Ecuador model, we calculated the probability of a major osteoporotic fracture and a female hip fracture without any risk factor and without the inclusion of BMD. The probabilities were calculated in 5-year intervals from 40 to 90 years. The probabilities of major fractures and hip fractures were calculated in 3 different scenarios: 1. History of previous fracture without the inclusion of BMD, 2. T score -2.5 SD without other clinical risk factors, 3. T score -1.5 SD without other clinical risk factors.
Results:
In women without risk factors, the probability of a major osteoporotic fracture increased with age from 0.4% at 40 years to 7.3% at 90 years. The probability of hip fracture increased with age from 0% at 40 years to 3.6% at 90 years. The probability of a major osteoporotic fracture increased in women with a T score of -2.5 SD from 0.9% at 40 years to 5.5% at 90 years; with a T-score of -1.5 SD, from 0.6% at 40 years to 3.9% at 90 years.
Conclusion:
Data shows the importance of applying tools such as FRAX, specific for each country and also the creation of evaluation and intervention curves that allow discerning according to each patient the need for the use of resources such as DXA and specific treatments.
Palavras-chave : Assessment thresholds; FRAX; Intervention threshold; Ecuador; Osteoporosis.