Serviços Personalizados
Journal
Artigo
Indicadores
- Citado por SciELO
- Acessos
Links relacionados
- Citado por Google
- Similares em SciELO
- Similares em Google
Compartilhar
Infectio
versão impressa ISSN 0123-9392
Resumo
MONCAYO-ORTIZ, José-Ignacio et al. Correlation between detection of superantigens and oxacillin resistance of Staphylococcus aureus in hospital isolates . Infect. [online]. 2015, vol.19, n.3, pp.109-114. ISSN 0123-9392. https://doi.org/10.1016/j.infect.2015.02.004.
Objective: To establish the relationship between the detection of superantigens (MSSA) and Staphylococcus aureus resistance to oxacillin in hospital isolates. Material and methods: In 81 isolates of Staphylococcus aureus of hospital origin, an oxacillin susceptibility test was performed by an automated system and 22 superantigenic genes were obtained using single and multiplex PCR. Results: The MRSA was 38.3%. All MRSA isolates carried one or more genes for superantigens and 92.0% of MSSA. The numbers of genotypes for the 2 groups were variable, but the most important finding was that the egc cluster was detected only in MRSA (48.4%). The non-classic genes more often detected in MRSA were sem (53.1%) and seg (28.4%); in MSSA they were sem (37.0%) and seq (30.9%). The gen classic sec (13.6%) was more prevalent in MSSA and in MRSA; the classic genes were very low in frequency. For all genes, the genes: seg , sej , sen , seo and seq showed statistically significant differences between MRSA and MSSA isolates. Conclusion: This study did not reveal a clear relationship between the detection of superantigens and oxacillin susceptibility (MRSA vs. MSSA). Although the number of genotypes varied, the presence of egc cluster only in the MRSA isolate was an important finding. Further studies are needed to establish the importance of the egc cluster.
Palavras-chave : Staphylococcus aureus; Superantigen; Enterotoxins; Methicillin-Resistant Staphylococcus aureus; Methicillin-Sensitive Staphylococcus aureus; Oxacillin.