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Universitas Medica
versão impressa ISSN 0041-9095versão On-line ISSN 2011-0839
Resumo
BERMUDEZ BERMUDEZ, Melisa et al. Manifestations in the Oral Cavity and Face Associated with COVID-19. Univ. Med. [online]. 2021, vol.62, n.3, pp.115-131. Epub 30-Jun-2021. ISSN 0041-9095. https://doi.org/10.11144/javeriana.umed62-3.mcbc.
Objective:
To describe and analyze case reports and published studies in which a possible relationship between COVID-19 and mucocutaneous lesions in the oral cavity and face is presented.
Methodology:
A review was performed in Pubmed, Google Scholar, ProQuest, and Medline Complete databases, 56 articles were selected reporting mucocutaneous manifestations in oral cavity and face associated to COVID-19.
Results:
We found 91 reported cases with mucocutaneous manifestations in oral cavity and face, associated with COVID-19. Eighteen percent of the patients presented lesions at both facial and oral levels. The cheeks were the most affected areas representing 16 % and of oral lesions the most affected site was the tongue with 26 %.
Conclusion:
According to the findings, the presence of mucocutaneous manifestations in face and oral cavity are associated with SARS-CoV-2 infection. It is expected that tissues with higher expression of ECA2 and TMPRSS2 are more susceptible to infection by SARS-CoV-2 and therefore present some type of lesion. Among the oral tissues with higher expression of these molecules, the tongue was described, which would favor a higher prevalence of lesions.
Palavras-chave : COVID-19; facial; mucous membrane; oral manifestations.