Serviços Personalizados
Journal
Artigo
Indicadores
- Citado por SciELO
- Acessos
Links relacionados
- Citado por Google
- Similares em SciELO
- Similares em Google
Compartilhar
Biomédica
versão impressa ISSN 0120-4157versão On-line ISSN 2590-7379
Resumo
BARRIOS, Katherine; PATINO, Óscar; MUNOZ, Nelson e MONERIZ, Carlos. Congenital Langerhans cell histiocytosis. Biomed. [online]. 2020, vol.40, n.3, pp.464-471. Epub 30-Jun-2020. ISSN 0120-4157. https://doi.org/10.7705/biomedica.5150.
Langerhans cell histiocytosis is a rare pathology with different clinical manifestations in the neonatal period ranging from isolated bone lesions to systemic compromise.
We report a case of Langerhans cell histiocytosis including a literature review focused on the clinical manifestations, diagnosis, and treatment. A one-month-old patient was brought to medical consultation with lymphadenopathy and skin lesions, which were initially managed as an infectious pathology. The disease continued its progression without improvement with the treatment until the patient died due to respiratory failure.
The lymph node and skin biopsies revealed infiltration of atypical cells with positive immunohistochemistry for S1OO, CD1, and CD68 confirming Langerhans cell histiocytosis. This disorder represents a great challenge and, therefore, it is important to alert and sensitize medical teams about it for timely diagnosis and management.
Palavras-chave : Langerhans cells; histiocytosis; infant, newborn; infant; Colombia.