Abstract

BENAVIDES, Víctor Alfonso et al. Determinants of adherence to antihypertensive treatment of adults ≥ 35 years of age. Univ. Salud [online]. 2013, vol.15, n.2, pp.123-135. ISSN 0124-7107.

Introduction: Hypertension is a prevalent condition and a risk factor for morbidity and mortality around the world. The aim of this study is to establish the adherence determinants to antihypertensive treatment in adults over 35 from Pasto, Colombia. Methods: A cross-sectional study was conducted to establish the adherence determinants to antihypertensive pharmacotherapy in 128 adults at "Centro de Salud Lorenzo de Aldana". The adherence evaluation was made through the Morisky-Green test in its Spanish version. A descriptive analysis was used for demographic variables, and a logistic regression was performed to calculate a dichotomous outcome by adherence determinants. Results: The study sample consisted of 40 (31.3%) men and 88 (68.8%) women who are hypertensive patients. The percentage of adherence to medication was 41.4%. Male patients were more likely to be adherent to hypertensive treatment when they used more than one antihypertensive drugs such as angiotensin converting enzyme inhibitors, calcium channel blockers and diuretics (OR:4.16; 95% CI:0.34, 5.61), when they were married (OR:2.97; 95%CI:0.72, 11.73), and when they were hospitalized (OR:1.92; 95% CI:0.11, 33.30). However, female patients were adherent when they did not have comorbidity (OR: 4.27; 95%CI: 0.81, 22.49), when they were 35 to 45 years old (OR:4.0; 95%CI:0.39, 40.05), and when they were single (OR:2.56; 95%CI:1.03, 6.38). Conclusions: These findings suggest that adherence determinants to antihypertensive treatment may depend on gender.

Keywords : Hypertension; medication adherence; antihypertensive agents; comorbidity; adult; epidemiologic factors.

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